Nurses And DoctorsThe Medical News Source

New data from a large Swedish cohort suggest that screening mammography in women aged 40-49 years reduced the risk of breast cancer mortality by 26%, compared with women in that age group who were not screened. The results were presented Sept. 29 during a press briefing in advance of the annual Breast Cancer Symposium sponsored by the American Society of Clinical Oncology.

The insulin-like growth factor 1 receptor may offer a much-needed therapeutic target for triple-negative breast cancer, which can be notoriously difficult to treat.

An intensive lifestyle intervention produced significant improvements in weight, cardiovascular fitness, blood pressure, hemoglobin A, triglycerides, and HDL-cholesterol, which were largely maintained throughout 4 years of follow-up, according to a report in the Sept. 27 issue of the Archives of Internal Medicine.

Although the Food and Drug Administrations decision to keep rosiglitazone on the market with a risk management program in place that preserves some access to the controversial diabetes drug, the plan is expected to squelch most prescribing and therefore, could have an effect that approaches that in Europe, where it will no longer be marketed.

Newest postings (September 22, 2010):
Basic Sciences Informationist, Welch Medical Library, Johns Hopkins University; Clinical Informationist, Welch Medical Library, Johns Hopkins University; Public Health Informationist, Welch Medical Library, Johns Hopkins University. The MLANET job page is updated weekly on Wednesdays. Jobs appear chronologically, with the most recent postings at the top of the page, and then alphabetically by state. (Source: Medical Library Association News)

For patients with severe aortic stenosis who cannot withstand surgery, transcatheter aortic valve implantation markedly reduces mortality from any cause, cardiovascular mortality, the need for hospitalization, and cardiac symptoms, according to a report from the PARTNER trial published online Sept. 22 in the New England Journal of Medicine.

Antipsychotic drugs are associated with an almost one-third (32%) greater risk of venous thromboembolism, according to results of a nested case-control study of more than 100,000 primary care patients in the United Kingdom. The study was published online Sept. 21 in the British Medical Journal.

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SILVER SPRING, Md. (EGMN) A Food and Drug Administration advisory panel on Sept. 20 unanimously voted to recommend that dabigatran, an orally administered direct thrombin inhibitor, be approved for reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.

The National Library of Medicine, the world’s largest medical library and an arm of the National Institutes of Health, today released a new API Web page. An API is a set of routines that an application uses to request and carry out lower-level services performed by a computer’s operating system. (Source: NLM General Announcements)